The Dark Side of Inspirational Pasts: An Investigation of Nostalgia in Right-Wing Populist Communication

In recent years, research found that populism employed a new strategy by using nostalgia, a sentimental longing for the past, as a communication tool to persuade citizens to support their political agendas. In populist campaigns, nostalgia is used to affectively link (alleged) crises with longing for a cherished past. In this article, we applied a mixed-methods approach to understand how populists exploit nostalgia in their communication and how nostalgic rhetoric has the potential to persuade people to support their claims. In Study 1, we conducted a case study based on a qualitative content analysis of Alternative for Germany’s (AfD) online election campaign in the 2019 Thuringia election in East Germany. The analysis revealed that the campaign was built around the nostalgic narrative of the 1989 peaceful revolution as a proud historical moment for former German Democratic Republic citizens while at the same time creating a sense of crisis supposedly caused by false post-reunification politics. To further investigate the persuasiveness of nostalgia, Study 2 used a statement from the campaign and found that participants tended to agree more with populist statements if they contained nostalgic rhetoric (compared to non-nostalgic populist and control rhetoric). These findings suggest that right-wing populists can effectively exploit nostalgia and that it may ‘sugarcoat’ populist messages

Film Language Integrated Learning:A Usage-Inspired L2 Teaching Approach

Recent decades have seen an increase in the use of authentic video materials in second or foreign language teaching (L2). Film Language Integrated Learning (FLIL) is a usage-inspired L2 teaching approach that seeks to combine insights from the dynamic usage-based (DUB) approach to language with the use of these video materials in the classroom. Consequently, FLIL uses popular films to provide (nearly) authentic, contextualised target language input. This input is scaf-folded through repetition, a focus on chunks and visual support, such as captions and additional images. This chapter discusses two variants of the FLIL approach: stand-alone and embedded FLIL. Stand-alone FLIL incorporates short film scenes into a somewhat fixed instructional sequence that forms a complete teaching approach in itself. Three empirical studies, Hong (2013), Koster (2015) and Irshad (2015), provide evidence for its effectiveness on broad General English Proficiency (GEP) measures and writing proficiency. Embedded FLIL uses elements from stand-alone FLIL inside a broader language course, which allows for more learner output. Four embedded FLIL courses for Italian, German and Russian as a foreign language are currently taught at the University of Groningen (the Netherlands), and are generally perceived favourably by students. Further development of and research into FLIL implementa-tions could focus specifically on testing free spoken proficiency, teasing apart the impact of different elements of the FLIL approach and match-ing materials with learner needs

Extracellular Proteome and Citrullinome of the Oral Pathogen Porphyromonas gingivalis

Porphyromonas gingivalis is an oral pathogen associated with the inflammatory disease periodontitis. Periodontitis and P. gingivalis have been associated with rheumatoid arthritis. One of the hallmarks of rheumatoid arthritis is the loss of tolerance against citrullinated proteins. Citrullination is a post translational modification of arginine residues, leading to a change in structure and function of the respective protein. This modification, which is catalyzed by peptidylarginine deiminases (PADs), plays a role in several physiological processes in the human body. Interestingly, P. gingivalis secretes a citrullinating enzyme, known as P. gingivalis PAD (PPAD), which targets bacterial and human proteins. Because the extent of P. gingivalis protein citrullination by PPAD was not yet known, the present study was aimed at identifying the extracellular proteome and citrullinome of P. gingivalis. To this end, extracellulai proteins of two reference strains, two PPAD-deficient mutants, and three clinical isolates of P. gingivalis were analyzed by mass spectrometry. The results uncovered substantial heterogeneity in the extracellular proteome and citrullinome of P. gingivalis, especially in relation to the extracellular detection of typical cytoplasmic proteins. In contrast, the major virulence factors of P. gingivalis were identified in all investigated isolates, although their citrullination was shown to vary. This may be related to post-translational processing of the PPAD enzyme. Altogether, our findings focus attention on the possible roles of 6 to 25 potentially citrullinated proteins, especially the gingipain RgpA, in periodontitis and rheumatoid arthritis.</p

Volume-rendered optical coherence tomography angiography during ocular interventions: Advocating for noninvasive intraoperative retinal perfusion monitoring.

We aimed to test for feasibility of volume-rendered optical coherence tomography angiography (OCTA) as a novel method for assessing/quantifying retinal vasculature during ocular procedures and to explore the potential for intraoperative use. Thirty patients undergoing periocular anaesthesia were enrolled, since published evidence suggests a reduction in ocular blood flow. Retinal perfusion was monitored based on planar OCTA image-derived data provided by a standard quantification algorithm and postprocessed/volume-rendered OCTA data using a custom software script. Overall, imaging procedures were successful, yet imaging artifacts occurred frequently. In interventional eyes, perfusion parameters decreased during anaesthesia. Planar image-derived and volume rendering-derived parameters were correlated. No correlation was found between perfusion parameters and a motion artifact score developed for this study, yet all perfusion parameters correlated with signal strength as displayed by the device. Concluding, volume-rendered OCTA allows for noninvasive three-dimensional retinal vasculature assessment/quantification in challenging surgical settings and appears generally feasible for intraoperative use

No Obvious Role for Suspicious Oral Pathogens in Arthritis Development

A particular role for Porphyromonas gingivalis (Pg) and Aggregatibacter actinomycetemcomitans (Aa) has been suggested in periodontitis and rheumatoid arthritis (RA), as these bacteria could initiate the formation of rheumatoid factor (RF) and anticitrullinated protein autoantibodies (ACPA). We assessed whether serum antibodies against Pg and Aa in RA patients and non-RA controls reflect the subgingival presence of Pg and Aa, and evaluated the relationship of these antibodies to the severity of periodontal inflammation and RA-specific serum autoantibodies. In 70 Indonesian RA patients and 70 non-RA controls, the subgingival presence of Pg and Aa was assessed by bacterial 16S rRNA gene sequencing, and serum IgG levels specific for Pg and Aa were determined. In parallel, serum levels of ACPA (ACPA:IgG,IgA) and RF (RF:IgM,IgA) were measured. The extent of periodontal inflammation was assessed by the periodontal inflamed surface area. In both RA patients and the controls, the presence of subgingival Pg and Aa was comparable, anti-Pg and anti-Aa antibody levels were associated with the subgingival presence of Pg and Aa, and anti-Pg did not correlate with ACPA or RF levels. The subgingival Pg and Aa were not related to RA. No noteworthy correlation was detected between the antibodies against Pg and Aa, and RA-specific autoantibodies

Characterizing and optimizing qubit coherence based on SQUID geometry

The dominant source of decoherence in contemporary frequency-tunable superconducting qubits is 1/$f$ flux noise. To understand its origin and find ways to minimize its impact, we systematically study flux noise amplitudes in more than 50 flux qubits with varied SQUID geometry parameters and compare our results to a microscopic model of magnetic spin defects located at the interfaces surrounding the SQUID loops. Our data are in agreement with an extension of the previously proposed model, based on numerical simulations of the current distribution in the investigated SQUIDs. Our results and detailed model provide a guide for minimizing the flux noise susceptibility in future circuits.Comment: 14 pages, 6 figure